Publications & Works

Publication Network
Articles 32
All (32)
SCI-E, SSCI, AHCI (23)
SCI-E, SSCI, AHCI, ESCI (26)
ESCI (2)
Scopus (29)
TRDizin (1)
Other Publications (1)

1. Cys340Ser Mutation Abolishing S-Nitrosylation Drives GRK2 Mitochondrial Localization and Dysfunction

KAYKI MUTLU G., Kereliuk S. M., Hoteit M., Chuprun J. K., Mendes U., OLĞAR Y., et al.
Cells , vol.15, no.5, 2026 (SCI-Expanded, Scopus) identifier identifier

2. A year in pharmacology: new drugs approved by the US food and drug administration in 2025

KAYKI MUTLU G., Aksoyalp Z. S., Wojnowski L., Michel M. C.
Naunyn-Schmiedeberg's Archives of Pharmacology , 2026 (SCI-Expanded, Scopus) Creative Commons License identifier identifier

3. Linking phospholipid metabolism to septic cardiomyopathy via HIF-1α overactivation.

Kayki Mutlu G., Koch W. J.
Nature cardiovascular research , vol.4, no.9, pp.1036-1037, 2025 (Peer-Reviewed Journal) identifier identifier

4. Mitochondrial GRK2 dependent regulation of myocardial cellular and transcriptional composition after ischemic injury

Slone S., Chuprun K., Tucker N., Haynes N., KAYKI MUTLU G., Roy R., et al.
CIRCULATION RESEARCH , vol.137, no.SUPPL_1, 2025 (SCI-Expanded, Scopus) identifier

5. A year in pharmacology: new drugs approved by the US Food and Drug Administration in 2024

Aksoyalp Z. S., KAYKI MUTLU G., Wojnowski L., Michel M. C.
Naunyn-Schmiedeberg's Archives of Pharmacology , vol.398, no.5, pp.5077-5099, 2025 (SCI-Expanded, Scopus) identifier identifier identifier

6. Sitagliptin does not improve isoprenaline-induced cardiac contractility in streptozotocin-induced diabetic rats

Boztas C. U., Erdogan B. R., Muderrisoglu A. E., KAYKI MUTLU G., YEŞİLYURT DİRİCAN Z. E., Karaomerlioglu I., et al.
ISTANBUL JOURNAL OF PHARMACY , no.3, pp.359-367, 2024 (ESCI, TRDizin) identifier

7. A year in pharmacology: new drugs approved by the US Food and Drug Administration in 2023

KAYKI MUTLU G., Aksoyalp Z. S., Wojnowski L., Michel M. C.
Naunyn-Schmiedeberg's Archives of Pharmacology , vol.397, no.5, pp.2949-2970, 2024 (SCI-Expanded, Scopus) Creative Commons License identifier identifier

8. Cardiac adrenergic receptors and GRKs: mitochondrial modulation in the heart

KAYKI MUTLU G., ARIOĞLU İNAN E.
Current Opinion in Physiology , vol.37, 2024 (ESCI, Scopus) identifier

9. A year in pharmacology: new drugs approved by the US Food and Drug Administration in 2022

KAYKI MUTLU G., Aksoyalp Z. S., Wojnowski L., Michel M. C.
Naunyn-Schmiedeberg's Archives of Pharmacology , vol.396, no.8, pp.1619-1632, 2023 (SCI-Expanded, Scopus) Creative Commons License identifier identifier

10. Novel roles for G protein-coupled receptor kinases in cardiac injury and repair

Kayki-Mutlu G., Koch W. J.
BIOCHEMICAL SOCIETY TRANSACTIONS , no.2, pp.715-724, 2023 (SCI-Expanded, Scopus) identifier identifier

11. Sex Differences in Glucose Homeostasis

ARIOĞLU İNAN E., KAYKI MUTLU G.
SEX AND GENDER EFFECTS IN PHARMACOLOGY , pp.219-239, 2023 (SCI-Expanded, Scopus) Sustainable Development identifier identifier

12. Sponging Away Cardiac Injury A Natural Compound Shows Cardioprotective Promise

Kayki-Mutlu G., Ferrero K. M., Koch W. J.
JACC-BASIC TO TRANSLATIONAL SCIENCE , vol.7, no.11, pp.1117-1119, 2022 (SCI-Expanded, Scopus) identifier identifier identifier

13. A year in pharmacology: new drugs approved by the US Food and Drug Administration in 2021

KAYKI MUTLU G., Aksoyalp Z. S., Wojnowski L., Michel M. C.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY , vol.395, no.8, pp.867-885, 2022 (SCI-Expanded, Scopus) Creative Commons License Sustainable Development identifier identifier identifier

14. Uncovering a role of β3-adrenoceptors in control of bladder size

Mutlu K. G., Ferrero K., Inan A. E., Michel M. C., Koch W.
EUROPEAN UROLOGY , vol.79, 2021 (SCI-Expanded, Scopus) identifier

15. A year in pharmacology: new drugs approved by the US Food and Drug Administration in 2020

KAYKI MUTLU G., Michel M. C.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY , vol.394, no.5, pp.839-852, 2021 (SCI-Expanded, Scopus) Creative Commons License Sustainable Development identifier identifier identifier

16. Nitric Oxide and S-Nitrosylation in Cardiac Regulation: G Protein-Coupled Receptor Kinase-2 and beta-Arrestins as Targets

Kayki-Mutlu G., Koch W. J.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , vol.22, no.2, 2021 (SCI-Expanded, Scopus) Creative Commons License identifier identifier identifier

17. Cardiac and Vascular alpha(1)-Adrenoceptors in Congestive Heart Failure: A Systematic Review

KAYKI MUTLU G., Papazisi O., Palmen M., Danser A. H. J., Michel M. C., ARIOĞLU İNAN E.
CELLS , vol.9, no.11, 2020 (SCI-Expanded, Scopus) Creative Commons License Sustainable Development identifier identifier identifier

18. Beta-3 adrenoceptors: A potential therapeutic target for heart disease

KAYKI MUTLU G., Karaomerlioglu I., ARIOĞLU İNAN E., Altan V. M.
EUROPEAN JOURNAL OF PHARMACOLOGY , vol.858, 2019 (SCI-Expanded, Scopus) Sustainable Development identifier

19. Cardiac beta(3)-adrenoceptors-A role in human pathophysiology?

ARIOĞLU İNAN E., KAYKI MUTLU G., Michel M. C.
BRITISH JOURNAL OF PHARMACOLOGY , vol.176, no.14, pp.2482-2495, 2019 (SCI-Expanded, Scopus) Sustainable Development identifier identifier identifier

20. The effect of nitric oxide synthase on beta 3 adrenoceptor mediated relaxation in STZ diabetic rat heart

KAYKI MUTLU G., Karaömerlioğlu I., ARIOĞLU İNAN E.
Ankara Universitesi Eczacilik Fakultesi Dergisi , vol.43, no.1, pp.64-71, 2019 (Scopus) Sustainable Development identifier

21. Direct effects of epigallocatechin gallate (EGCG) on isolated rat cardiomyocytes under normal and high glucose concentrations Epigallokateşin Gallat (EGCG)'in normal ve yüksek glukoz ortaminda izole siçan kardiyomyositleri üzerindeki direkt etkileri

KAYKI MUTLU G., Yeşilyurt Z. E., Erdoğan B. R., Karaömerlioğlu I., Müderrisoğlu A. E., ARIOĞLU İNAN E., et al.
Ankara Universitesi Eczacilik Fakultesi Dergisi , vol.43, no.1, pp.72-78, 2019 (Scopus) Sustainable Development identifier

22. EPİGALLOKATEŞİN GALLAT (EGCG)’IN NORMAL VE YÜKSEK GLUKOZ ORTAMINDA İZOLE SIÇAN KARDİYOMYOSİTLERİ ÜZERİNDEKİ DİREKT ETKİLERİ

KAYKI MUTLU G., Yeşilyurt Z. E., ERDOĞAN B. R., KARAÖMERLİOĞLU İ., Müderrisoğlu A. E., ARIOĞLU İNAN E., et al.
Ankara Üniversitesi Eczacılık Fakültesi Dergisi , vol.43, no.1, 2019 (Scopus)

23. Role of the beta(3)-adrenergic receptor subtype in catecholamine-induced myocardial remodeling

Mutlu G., ARIOĞLU İNAN E., Karaomerlioglu I., ALTAN V. M., YERSAL N., KORKUSUZ P., et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY , vol.446, no.1-2, pp.149-160, 2018 (SCI-Expanded, Scopus) identifier identifier identifier

24. Aging related functional and structural changes in the heart and aorta: MitoTEMPO improves aged-cardiovascular performance

OLĞAR Y., DEĞİRMENCİ S., DURAK A., BİLLUR D., CAN B., KAYKI MUTLU G., et al.
Experimental Gerontology , vol.110, pp.172-181, 2018 (SCI-Expanded, Scopus) Sustainable Development identifier identifier identifier

25. Onset of decreased heart work is correlated with increased heart rate and shortened QT interval in high-carbohydrate fed overweight rats

DURAK A., OLĞAR Y., TUNCAY E., Karaomerlioglu I., Mutlu G., ARIOĞLU İNAN E., et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY , vol.95, no.11, pp.1335-1342, 2017 (SCI-Expanded, Scopus) identifier identifier identifier

26. beta(3)-Adrenoceptor-mediated responses in diabetic rat heart

KAYKI MUTLU G., ARIOĞLU İNAN E., ÖZAKCA GÜNDÜZ I., ÖZÇELİKAY A. T., Altan V. M.
GENERAL PHYSIOLOGY AND BIOPHYSICS , vol.33, no.1, pp.99-109, 2014 (SCI-Expanded, Scopus) Creative Commons License Sustainable Development identifier identifier identifier

27. The role of insulin-thyroid hormone interaction on beta-adrenoceptor-mediated cardiac responses

ARIOĞLU İNAN E., ÖZAKCA GÜNDÜZ I., KAYKI MUTLU G., SEPİCİ DİNÇEL A., Altan V. M.
EUROPEAN JOURNAL OF PHARMACOLOGY , vol.718, no.1-3, pp.533-543, 2013 (SCI-Expanded, Scopus) Sustainable Development identifier identifier identifier

28. Nebivolol prevents desensitization of beta-adrenoceptor signaling and induction of cardiac hypertrophy in response to isoprenaline beyond beta(1)-adrenoceptor blockage

ÖZAKCA GÜNDÜZ I., ARIOĞLU İNAN E., Esfahani H., Altan V. M., Balligand J., KAYKI MUTLU G., et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY , vol.304, no.9, 2013 (SCI-Expanded, Scopus) identifier identifier identifier

29. Cardioprotective effects of 44Bu, a newly synthesized compound, in rat heart subjected to ischemia/reperfusion injury

Basgut B., KAYKI MUTLU G., Bartosova L., ÖZAKCA GÜNDÜZ I., Seymen A., KANDİLCİ H. B., et al.
EUROPEAN JOURNAL OF PHARMACOLOGY , vol.640, no.1-3, pp.117-123, 2010 (SCI-Expanded, Scopus) identifier identifier identifier

30. Diyabetik Sıçan Kalbinde İskemi/Reperfüzyon Hasarına Karşı Artmış Tolerans Kalp Atım Hızından Bağımsızdır

ALTUNKAYNAK ÇAMCA H. Ö., ARIOĞLU İNAN E., ÖZAKCA GÜNDÜZ I., KAYKI MUTLU G., ÖZÇELİKAY A. T.
Ankara Üniversitesi Eczacılık Fakültesi Dergisi , vol.38, no.4, pp.305-315, 2009 (Scopus) Sustainable Development

31. Increased tolerance against ischemia reperfusion injury in diabetic rat heart is independent from heart rate

ALTUNKAYNAK H. Ö., ARIOĞLU İNAN E., ÖZAKCA I., KAYKI MUTLU G., ÖZÇELİKAY A. T.
Journal of Faculty of Pharmacy of Ankara University , vol.38, no.4, pp.305-315, 2009 (Peer-Reviewed Journal) Sustainable Development

32. INCREASED TOLERANCE AGAINST ISCHEMIA/REPERFUSION INJURY in DIABETIC RAT HEART IS INDEPENDENT from HEART RATE DİYABETİK SIÇAN KALBİNDE İSKEMİ/ REPERFÜZYON HASARINA KARŞI ARTMIŞ TOLERANS KALP ATIM HIZINDAN BAǦIMSIZDIR

Altunkaynak H. Ö., Arioǧlu E., ÖZAKCA GÜNDÜZ I., Kayki G., ÖZÇELİKAY A. T.
Ankara Universitesi Eczacilik Fakultesi Dergisi , vol.38, no.4, pp.305-315, 2009 (Scopus) Creative Commons License Sustainable Development identifier
Papers Presented at Peer-Reviewed Scientific Conferences 26

1. GRK2 'nin kardiyak patolojilerdeki metabolik rolleri

Kaykı Mutlu G.
9th European Section Meeting of the International Academy of Cardiovascular Sciences (IACS-ES), Timisoara, Romania, 4 - 07 October 2023, (Unpublished)

2. Mitochondrial GRK2 Dependent Regulation of the Cellular and Transcriptional Composition after Myocardial Infarction

Slone S., Chuprun K., Kayki-Mutlu G., Roy R., Ibetti J., Gao E., et al.
Annual meeting of the American-Society-for-Pharmacology-and-Experimental-Therapeutics (ASPET), Missouri, United States Of America, 18 - 21 May 2023, (Summary Text) Sustainable Development identifier

3. GRK2 in the Mitochondria: Uncovering Novel Mechanism in Heart Failure

Ferrero K., KAYKI MUTLU G., Pfleger J., Tilley D., Koch W.
AHA Scientific Sessions, 13 - 17 November 2020, (Summary Text)

4. Effects of Cardiac ß3-Adrenoceptors on the Inhibition of G Protein-Coupled Receptor Kinase 2 via S-Nitrosylation

KAYKI MUTLU G., Roy R., Lucchese A. M., Gao E., Koch W.
Basic Cardiovascular Science Scientific Sessions 2020, 27 - 30 July 2020, (Summary Text)

5. Mitokondriyal GRK2 lokalizasyonunun önlenmesinin myokard infarktüsünde koruyucu etkileri

KAYKI MUTLU G., Koch W.
25.Ulusal Farmakoloji Kongresi, Turkey, 4 - 07 November 2019, (Summary Text)

6. Changes in β-adrenoceptor mediated responses and protein expression in dapagliflozin treated HFD and low dose STZ diabetic rat heart

KARAÖMERLİOĞLU İ., Yeşilyurt Z. E., ERDOĞAN B. R., KAYKI MUTLU G., Müderrisoğlu A. E., ALTAN V. M., et al.
CVOT Summit 2019, Munich, Germany, 24 - 25 October 2019, (Summary Text) Sustainable Development

7. Effects of aliskiren treatment on cardiac myocyte dysfunction in a rat model of insulin resistance

CAN T., TARHAN N., OZANSOY F. G., CEYLAN IŞIK A. F., KAYKI MUTLU G., ARI N.
12th International Symposium on Pharmaceutical Sciences (ISOPS-12), Ankara, Turkey, 26 - 29 June 2018, pp.133, (Summary Text)

8. Effects Of Three Different Flavonoids On CardiacContractility Under High Glucose Concentrations

KAYKI MUTLU G., Yeşilyurt Z. E., ERDOĞAN B. R., KARAÖMERLİOĞLU İ., Müderrisoğlu A. E., ARI N.
12thInternational Symposium On Pharmaceutical Sciences, 26 - 29 June 2018, (Summary Text)

9. Regulation of Na-K pump by β3-adrenergic receptors in aortas from noradrenaline-treated rats

KAYKI MUTLU G., Müderrisoğlu A. E., KARAÖMERLİOĞLU İ., ERDOĞAN B. R., ALTAN V. M., ARIOĞLU İNAN E.
Pharmacology 2017, Londrina, Brazil, 11 - 13 December 2017, (Summary Text)

10. The effects of leptin on cardiac function in streptozotocin diabetic rats

ARIOĞLU İNAN E., KAYKI MUTLU G., ERDOĞAN B. R., Müderrisoğlu A. E., KARAÖMERLİOĞLU İ., Yeşilyurt Z. E., et al.
Pharmacology 2017, Londrina, Brazil, 11 - 13 December 2017, (Summary Text) Sustainable Development

11. The effect of sitagliptin on beta-adrenoceptor-mediated cardiac responses in streptozotocin induced diabetic rats

UYAR BOZTAŞ C., ARIOĞLU İNAN E., MÜDERRİSOĞLU A. E., KAYKI MUTLU G., ERDOĞAN B. R., YEŞİLYURT Z. E., et al.
3rd CVOT (cardiovascular Outcome Trial) Summit Of The D CVD Study Group, Munich, Germany, 26 - 27 October 2017, (Summary Text) Sustainable Development

12. The Effect Of Dapagliflozin Treatment On Beta Adrenoceptor-mediated Responses In High Fat Fed Diabetic Rat Heart

KARAÖMERLİOĞLU İ., KAYKI MUTLU G., ÖZTÜRK N., ERDOĞAN B. R., MÜDERRİSOĞLU A. E., YEŞİLYURT Z. E., et al.
3rd CVOT (cardiovascular Outcome Trial) Summit Of The D CVD Study Group, Munich, Germany, 26 - 27 October 2017, (Summary Text) Sustainable Development

13. Altered heart function in high sucrose fed overweight rats: ın vivo and in vitro investigations

ARIOĞLU İNAN E., toy durak a., olgar Y., tuncay e., KAYKI MUTLU G., KARAÖMERLİOĞLU İ., et al.
DCVD Annual Meeting, 22 June - 24 July 2017, (Summary Text)

14. Altered Heart Function In HighSucrose-fed Overweight Rats: In Vivo And In Vitro Investigations

ARIOĞLU İNAN E., Toy Durak A., Olgar Y., Tuncay E., KAYKI MUTLU G., KARAÖMERLİOĞLU İ., et al.
DCVD Annual Meeting, Milan, Italy, 22 - 24 June 2017, (Summary Text)

15. β3–Adrenoseptör Alttipinin Katekolamin ile İndüklenen Kardiyak Hipertrofi Üzerindeki Rolü ve Na/K Pompası ile İlişkisi

KAYKI MUTLU G.
Türk Farmakoloji Derneği, Farmakoloji Eğitiminde Kuşaklararası Bilimsel Etkileşme Seminerleri, Turkey, 22 - 24 March 2017, (Full Text)

16. The effect of leptin treatment on in vivo cardiac parameters of streptozotocin induced diabetic rats

ARIOĞLU İNAN E., ERDOĞAN B. R., Müderrisoğlu E., KARAÖMERLİOĞLU İ., KAYKI MUTLU G., BEŞİKCİ A., et al.
9th Annual Meeting of the Diabetes and Cardiovascular Disease, 30 June - 02 July 2016, (Full Text) Sustainable Development

17. The Effect of Beta 3 ARs on Na K ATPase in Cardiac Hypertrophy

KAYKI MUTLU G., ARIOĞLU İNAN E., KARAÖMERLİOĞLU İ., ALTAN V. M.
7th European Congress of Pharmacology, 26 - 30 June 2016, (Summary Text)

18. The effect of 3 adrenoceptors on Na K pump modulation in noradrenaline incubated cardiomyocytes

KAYKI MUTLU G., ROCCHETTI M., ALTAN V. M., ZAZA A.
EHRA EUROPACE-CARDIOSTIM 2015, Milan, Italy, 21 - 24 June 2015, (Summary Text)

19. The effect of thyroid hormone insulin interaction on diabetic rat aorta.

ARIOĞLU İNAN E., ÖZAKCA I., KAYKI MUTLU G., KARAÖMERLİOĞLU İ., ALTAN V. M.
ISOPS-11, 9 - 12 June 2015, (Summary Text) Sustainable Development

20. 3 AR Modulation Of Cardiac Na K Pump In Diabetic Mice

KAYKI MUTLU G., ROCCHETTI M., ALTOMARE C., ALTAN V. M., ZAZA A.
7th Annual Meeting of the Diabetes and Cardiovascular Disease, Milan, Italy, 6 - 08 November 2014, (Summary Text) Sustainable Development

21. Beta 3 Adrenoceptor Mediated Responses In Diabetic Rat Thoracic Aorta

ARIOĞLU İNAN E., KAYKI MUTLU G., KARAÖMERLİOĞLU İ., ALTAN V. M.
7th Annual Meeting of the Diabetes and Cardiovascular Disease, Milan, Italy, 6 - 08 November 2014, (Summary Text) Sustainable Development

22. The possible contribution of thyroid hormones to insulin effect on beta adrenoceptor mediated cardiac responses in diabetic rats

ARIOĞLU İNAN E., ÖZAKCA I., KAYKI MUTLU G., SEPİCİ DİNÇEL A., ALTAN V. M.
D&CVD 2012, 15 - 17 November 2012 Sustainable Development

23. Increased tolerance by diabetes against ischemia reperfusion injury in rat heart is independent from heart rate

ALTUNKAYNAK H. Ö., ARIOĞLU İNAN E., ÖZAKCA I., KAYKI MUTLU G., ÖZÇELİKAY A. T.
International Symposium on New Approaches in Cardiovascular Disorders, NACD2011, 4 - 08 May 2011, (Summary Text) Sustainable Development

24. Cardioprotective effects of 44Bu, a newly synthesized compound, in rat heart subjected to ischemia/reperfusion injury

Özçelikay A. T., Başgut B., Kaykı Mutlu G., Özakca Gündüz I., Kandilci H. B., Uğur M., et al.
ISHR 20. World Congress, Kyoto, Japan, 13 - 16 May 2010, (Summary Text)

25. The effects of diabetes on B3-adrenoceptor-mediated cardiac responses

KAYKI MUTLU G., ARIOĞLU İNAN E., ÖZAKCA GÜNDÜZ I., ÖZÇELİKAY A. T., ALTAN V. M.
14th Annual Meeting of the European Council for Cardiovascular Research (ECCR), 9 - 11 October 2009, (Summary Text) Sustainable Development

26. The effects of diabetes on beta 3 adrenoceptor mediated cardiac responses

KAYKI MUTLU G., ARIOĞLU İNAN E., ÖZAKCA I., ÖZÇELİKAY A. T., ALTAN V. M.
14th Annual Meeting Of The European Council For Cardiovascular Research, Nice, France, 9 - 11 October 2009, vol.54, pp.1180, (Summary Text) Sustainable Development
Books 2

1. Differences in Glucose Homeostasis.

Arıoğlu İnan E., Kaykı Mutlu G.
in: Handbook of Experimental Pharmacology, Stella E. Tsirka,Maricedes Acosta-Martinez, Editor, Springer, London/Berlin , London, pp.219-239, 2023

2. Diuretic Agents

Arıoğlu İnan E., Kaykı Mutlu G.
in: Comprehensive Pharmacology, Terry Kenakin, Editor, Elsevier Science, Oxford/Amsterdam , North Carolina, pp.634-655, 2022
Metrics

Publication

60

Publication (WoS)

27

Publication (Scopus)

29

Citation (WoS)

258

H-Index (WoS)

10

Citation (Scopus)

277

H-Index (Scopus)

11

Citation (Scholar)

90

H-Index (Scholar)

2

Project

9

Open Access

9
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