Total oxidant status and oxidative stress are increased in infants with necrotizing enterocolitis

Aydemir C., Dilli D., Uras N., Ulu H. O., Oguz S. S., Erdeve O., ...More

JOURNAL OF PEDIATRIC SURGERY, vol.46, no.11, pp.2096-2100, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 11
  • Publication Date: 2011
  • Doi Number: 10.1016/j.jpedsurg.2011.06.032
  • Journal Name: JOURNAL OF PEDIATRIC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2096-2100
  • Keywords: Necrotizing enterocolitis, Antioxidants, Oxidative stress, Preterm neonate, PLATELET-ACTIVATING-FACTOR, NEONATAL-RAT MODEL, SEVERITY, DAMAGE, SUPPLEMENTATION, GENERATION, INTESTINE, INJURY, ALPHA
  • Ankara University Affiliated: Yes

Abstract

Background: Oxidative stress has been implicated in the pathogenesis of necrotizing enterocolitis (NEC). In this study, we compared the global oxidant/antioxidant status by measuring total antioxidant capacity (TAC), total oxidant status (TOS), and oxidative stress index (OSI) in preterm infants with NEC and with control preterms.