THE TOTAL ANTIOXIDANT CAPACITY MAY NOT BE RELATED TO BILIRUBIN AND URIC ACID LEVEL IN PATIENTS WITH BETA THALASSEMIA

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Karakas Z., Yilmaz Y., Celik D. D., Annayev A., Kuruca S. E.

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, vol.83, no.4, pp.373-377, 2020 (ESCI)

• Publication Type: Article / Article
• Volume: 83 Issue: 4
• Publication Date: 2020
• Doi Number: 10.26650/iuitfd.2020.0013
• Journal Name: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
• Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
• Page Numbers: pp.373-377
• Keywords: Beta-thalassemia, antioxidant capacity, oxidant capacity, endogenous antioxidant, CHILDREN
• Ankara University Affiliated: Yes

Abstract

Objective: Iron burden resulting from ineffective erythropoiesis and multiple transfusions can cause oxidative stress in patients with beta-thalassemia. Here we aimed to examine the total antioxidant and oxidant capacity (TAC and TOC) along with its relation to endogenous antioxidants (bilirubin and uric acid) in patients with beta-thalassemia.