Preservation of myocardial metabolism in acute coronary artery occlusions with retrograde coronary sinus perfusion and iloprost


Katircioglu S., Ulus A., Iscan Z., Yamak B., Saritas Z., Birincioglu L.

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, vol.59, no.3, pp.169-174, 1998 (SCI-Expanded, Scopus)

Abstract

A total of 12 healthy mongrel dogs were subjected to the study. The left anterior descending artery was occluded. The occlusion was done for 15 min. At the end of this period, without removing the occlusion, the heart was retroperfused for 3 h. Then, occlusion was removed and reperfusion was supplied. Animals were divided into two equal groups. Six animals received iloprost and the other six control did not receive any additional treatment. In the iloprost group, the drug was administered into the coronary sinus.